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Critical results

For critical results being sent internally within the Hospital, we provide a telephone service, 24 hours a day, seven days a week. 

All results will be telephoned 24 hours a day if they meet the criteria stated below.

 

Haematology

Inpatients

All haematology results meeting the criteria below will be phoned to the requesting clinician, except where the results are persistently abnormal. In these cases, only a change to results, that may affect patient management, will be phoned over.

Analyte

Hb

Platelet count

Suspected leukaemia

Neutrophils

Glandular fever screen

Malaria screen

Emergency Sickle Screen

INR

APTT Ratio

Fibrinogen

DDimer

Critical limit(s)

<70g/l  or >200g/l

<50 x 109/l or >1000 x 109/l

Blasts, high WBC, etc

<1.0 x 109/l  or >30 x 109/l

Positive

Positive

Positive or negative

>5.0

>4.5

<1.5g/l or >11g/l

>20.0ug/ml

GP results

All GP results meeting the critical criteria will be telephoned during the "normal working" day. Please refer to the discipline-specific sections for detailed information.

Results phoned to the out-of-hours service should also be phoned to the GP surgery the following morning to verify that action has been taken. All haematology results meeting the criteria in the table below will be phoned to the requesting clinician, or the out-of-hours service, except where the results are persistently abnormal. In these cases, only a change to results that may affect patient management will be phoned over.

If there is concern that the patient’s condition may result in the patient being contacted by an on-call clinician, this should be made clear to the patient during their appointment.

Analyte

Hb

Platelet count

Suspected leukaemia

Neutrophils

Malaria screen


Emergency Sickle Screen

INR

APTT Ratio

Fibrinogen

DDimer

Critical Limit(s)

<80g/l  or >200g/l

<50 x 109/l or >1000 x 109/l

Blasts, high WBC, etc

<1.0 x 109/l  or >30 x 109/l

Positive

Positive or negative

>5.0

>4.5

<1.5g/l or >11g/l


Any
result >=0.5ug/ml

Additional considerations

In addition to contacting the requesting clinician, the following cases will be promptly referred to a Consultant Haematologist for direct clinical liaison and advice:

  • newly presented leukaemia 
  • newly presented malaria infection
  • positive sickle haemoglobin screen in patients about to undergo anaesthesia
  • any low factor assay result for patients undergoing an emergency procedure
  • persistently prolonged isolated APTT or PT result where there is an acute bleeding risk to the patient (when the patient is not on anticoagulant therapy)

Chemical Pathology

Inpatients

For critical results being sent internally within the Hospital, we provide a telephone service, 24 hours a day, seven days a week. 

All results will be telephoned 24 hours a day if they meet the criteria stated in the table below. 

GP Results

The below table identifies the arrangements for telephoning GP results out-of-hours. The table indicates whether the results are telephoned to the GP out-of-hours service, or whether they are telephoned to the GP practise the following working day.

Therapeutic drug monitoring results will be telephoned (as specified below) if they are significantly outside the therapeutic range. It must be stressed, however, that the patient and not the biochemistry result should be treated. This is because therapeutic ranges are only guides and there is wide inter-individual variation.

List of Biochemistry Critical Phoning Limits

ANALYTE

LOWER LIMIT (and below)

HIGHER LIMIT (and above)

Source

Sodium (mmol/L)

120

<130 if <16yrs

150

RCPath 2017

RCPath 2017 for children as particular concern of risk of death in children with hypoNa

Potassium (mmol/L)

2.5

6.5

RCPath 2017

Potassium (mmol/L)

Heart Failure Nurses**

3.9

5.4

Barnsley and Rotherham local agreement

Potassium (mmol/L)

GP Patients†

 

6.0

When AKI >1

RCPath 2017

On new occurrences

Glucose (mmol/L)

2.5

25

(>15 if <16 years)

RCPath 2017

State 30mmol/L for GP known DM patients

Glucose results < 2.5 may be less crucial to phone immediately

Urea (mmol/L)

 

30  

(>10 if <16 years)

RCPath 2017
Creatinine (umol/L)

 

350

(>200 if <16 years)

RCPath 2017 (actually states 354 umol/L)   higher thresholds for known CKD or pt on dialysis.

Need specific local points for babies.

AKI

Level of 2 or above

 

All new occurrences

AKI†

GP Patients

 

1

When Potassium >6.0

RCPath 2017

All new occurrences

Serum Bicarbonate

10

 

RCPath 2017

GP only

Calcium - Adj (mmol/L)

1.8

3.0

Barnsley and Rotherham local agreement
PO4 (mmol/L)

0.3

 

RCPath 2017

Urgent inpatient, GP urgent, if OOH within 24 hours

Mg (mmol/L)

0.4

 

RCPath 2017
CK (U/L)

 

5000 unless ?MI

RCPath 2017
ALT (U/L)

 

735
(>500 if <16 years)*

RCPath 2017

 
AST (U/L)

 

510

(>500 if <16 years)*

RCPath 2017
Amylase (U/L)

 

590  

RCPath 2017
Lactate

 

>4.0

RCPath 2017
Lipase (U/L)

 

265

RCPath 2017
Bilirubin (umol/L)

 

300  

Barnsley and Rotherham local agreement
Conjugated Bilirubin (umol/L)

 

25

Neonates only

RCPath 2017

Triglyceride (mmol/L)

 

20

RCPath 2010
Ammonia (umol/L)

 

>40

Barnsley and Rotherham local agreement
Bile Acids*** (umol/L)

 

14

Barnsley and Rotherham local agreement
Iron (umol/L)

 

55

Barnsley and Rotherham local agreement
Uric Acid/Urate (umol/L)

 

340

Ante-natal only RCPath 2017
CRP (mg/L)

 

300  

RCPath 2017
Troponin I High Sensitivity (ng/L)

 

120

RCPath 2017, Local agreement
Troponin I High Sensitivity (ng/L) from GP

 

3

Local agreement
Cortisol (nmol/L)

50 unless part of O/N Dexamethasone suppression test

 

RCPath 2017
Cortisol (nmol/L) (SST 30 minutes)

250

 

RCPath 2017 – To be phoned by Biochemistry Consultant authorising the DFT
fT4 (pmol/L)

5

30  

Barnsley and Rotherham local agreement

In patient within 2 hours

GP/ Out pt next working day

fT3

 

10 if FT4 normal with suppressed TSH

Barnsley and Rotherham local agreement

In patient within 2 hours

GP/ Out pt next working day

TSH (mIU/L)

 

50 for 1st time

Barnsley and Rotherham local agreement

In patient within 2 hours

GP/ Out pt next working day

Paracetamol (mg/L)

 

If detected

Barnsley and Rotherham local agreement
Salicylate (mg/L)

 

If detected

Barnsley and Rotherham local agreement
Phenytoin (mg/L)

 

25

RCPath 2017
Carbamazepine (mg/L)

 

25

RCPath 2010
Theophylline (mg/L) 

 

25

RCPath 2017
Digoxin (ug/L)

 

2.5

RCPath 2017
Lithium (mmol/L)

 

1.5

RCPath 2017
Phenobarbitone (mg/L)

 

70

RCPath 2010
Valproate (mg/L)

 

150 for 1st time

Barnsley and Rotherham local agreement
PBG

 

Positive

Barnsley and Rotherham local agreement
Ethanol (mg/L)

 

Detected

Barnsley and Rotherham local agreement
Osmolality (mosm/kg)

270

300

Barnsley and Rotherham local agreement
Blood Gas††

All results where paper reports given

 

Barnsley and Rotherham local agreement
HbA1c

 

120mmol/mol

SY&B local Agreement for first-time HbA1c results without a glucose requested / not known diabetic

Please note, this list is not exhaustive. Results may be phoned if professional judgement by lab staff deems any changes to be significantly different to previous results, even though results are within the stated limits

Generally, the local agreement results in more results being phoned than is advised by the RCPath.

**Heart failure patients that have been identified with a sticker on the request card are phoned at lower potassium limits.

***Bile acids need to be phoned at all times, escalate to on-call Obs & Gynae registrar if no answer from antenatal unit.

† Potassium result >6.0 with AKI should be telephoned for all GP patients on first occurrence.